E-Freeze - Freezing of embryos in assisted conception: a randomised controlled trial evaluating the clinical and cost-effectiveness of a policy of freezing embryos followed by thawed frozen embryo transfer, compared with a policy of fresh embryo transfer

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Principal investigator: Abha Maheshwari (University of Aberdeen)
Collaborators: Stephen Troup (Liverpool Women's Hospital), Graham Scotland (University of Aberdeen), Madhurima Rajkohwa (Birmingham Women's Hospital), Nicholas Raine-Fenning (University of Nottingham), Nick Macklon (University of Southampton), Clare Lewis-Jones (Infertility Network, UK), Stuart Lavery (Hammersmith Hospital, Imperial College, London), Yacoub Khalaf (Guy's and St Thomas's NHS Foundation Trust), Stephen Harbottle (University of Cambridge), Rachel Cutting (Sheffield Teaching Hospitals NHS Foundation Trust), Arri Coomarasamy (Birmingham Women's NHS Foundation Trust), Tim Child (University of Oxford), Daniel Brison (Central Manchester University Hospital NHS trust), Siladitya Bhattacharya (University of Aberdeen), Pollyanna Hardy (NPEU (Former member)), Ed Juszczak (NPEU), Jenny Kurinczuk (NPEU)
Topics: Infertility
Funder: National Institute for Health Research Health Technology Assessment Programme
Start year: 2015
End year: 2019

Summary

E-Freeze is a multi-centre randomised controlled trial that compares fresh embryo transfer with frozen thawed embryo transfer for couples undergoing their first round of fertility treatment. The main aim is to understand if there is any difference in the chances of having a healthy baby.

Publications

Journal Articles

Maheshwari A, Bhattacharya S, Bowler U, Brison D, Child T, Cole C, Coomarasamy A, Cutting R, Harbottle S, Hardy P, Juszczak E, Khalaf Y, Kurinczuk JJ, Lavery S, Lewis-Jones C, Macklon N, Raine-Fenning NJ, Rajkohwa M, Scotland G, Troup S. Study protocol: E-freeze - freezing of embryos in assisted conception: a randomised controlled trial evaluating the clinical and cost effectiveness of a policy of freezing embryos followed by thawed frozen embryo transfer compared with a policy of fresh embryo transfer, in women undergoing in vitro fertilisation. Reproductive Health. [journal article]. 2019;16(1):81.